Abilify Drug
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Abilify - Aripiprazole
Generic Name : Aripiprazole
Brand Names : Abilify
What is Abilify or Aripiprazole?
Abilify (Aripiprazole) is prescribed to treat certain mental/mood disorders (e.g., bipolar disorder, schizophrenia). Aripiprazole is known as an antipsychotic drug (atypical type). It works by helping to restore the balance of certain natural chemicals in the brain (neurotransmitters). This medication can decrease hallucinations and improve the concentration. It helps the patient to think more clearly and positively. Aripiprazole can treat severe mood swings and prevent or decrease how often mood swings occur.
Indications
Abilify (Aripiprazole) is indicated to treat dementia-related behavior problems (e.g., agitation, aggression) when standard treatments (e.g., behavioral therapy, cholinesterase inhibitors) have not been successful. This drug should be used only for the condition for which it was prescribed.
Dosage
This medication should be taken by mouth with or without food, usually once daily or as directed by the doctor. If the patient is using the oral solution, the dose should be measured carefully using a medicine spoon or cup. Dosage is based on the medical condition of the patient and response to therapy. To reduce the risk of side effects, the doctor may gradually increase the dose. The doctor’s instructions should be followed carefully. If the patient is using the rapidly dissolving tablets, the patient should dry the hands before peeling back the foil on the blister pack to carefully remove a tablet. The tablet should not be pushed through the foil. The patient should place the tablet on the tongue, allow it to dissolve completely and then swallow it with saliva. The patient should not crush, split, or break the tablet before taking it. The patient should not remove the tablet from the blister pack until just before taking. No water is needed to take this medication. The patient should not take this medication more often or increase the dose without consulting the doctor. This medication should be used regularly in order to get the most benefit from it. The patient should not stop taking this medication without consulting the doctor.
Side effects
Consultation should be done with the doctor in case of having any of these side-effects:
- Dizziness, lightheadedness, nausea, vomiting, tiredness, excess saliva/drooling, blurred vision, weight gain, drowsiness and constipation may occur, fast/pounding heartbeat, fainting, mental/mood changes (e.g., increased anxiety, depression, suicidal thoughts), weakness, feelings of restlessness, mask-like facial expression, shakiness (tremors), muscle spasm/stiffness, trouble swallowing, swelling.
- This drug may rarely cause a condition known as tardive dyskinesia. In some cases, this condition may be permanent. Consultation should be done with the doctor immediately if the patient develops any unusual uncontrolled movements (especially of the face, mouth, tongue, arms or legs).
- This drug may infrequently cause a serious (rarely fatal) nervous system disorder (neuroleptic malignant syndrome). Consultation should be done with the doctor immediately if any of the following rare but very serious side effects: confusion, fever, fast heartbeat, muscle stiffness, increased sweating, change in the amount of urine.
Drug interactions
- This drug should not be used with the following medication because very serious interactions may occur: sibutramine.
- Before using this medication, consultation should be done with the doctor or pharmacist of all prescription and nonprescription/herbal products the patient is using, especially of: dopamine agonists (e.g., bromocriptine), drugs for treating high blood pressure (e.g., alpha blockers such as prazosin, calcium channel blockers such as diltiazem, "water pills"-diuretics such as hydrochlorothiazide), levodopa, drugs affecting liver enzymes that may remove aripiprazole from the body (e.g., azole antifungals including ketoconazole and itraconazole, quinidine, certain anti-seizure drugs including carbamazepine, ssri antidepressants including fluoxetine and paroxetine).
- Proper consultation should be done with the doctor in case of using drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenytoin), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).
- The patient should check the labels on all the medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness.
Overdose
If overdose is suspected, the patient should contact the local poison control center or emergency room immediately. Symptoms of overdose may include: very fast heartbeat, loss of consciousness.
Precautions
Before taking Abilify (Aripiprazole), consultation should be done with the doctor or pharmacist if:
- If allergic to it; or if having any other allergies, problems with blood flow in the brain (cerebrovascular disease, stroke), a severe loss of body water (dehydration), diabetes, heart problems (e.g., low blood pressure, coronary artery disease, heart failure, irregular heartbeat), nervous system problems (e.g., dementia, nms, seizures), obesity, trouble swallowing, alcohol/drug abuse.
- This drug may cause dizziness, drowsiness or temporary blurred vision. The patient should use caution while engaging in activities requiring alertness or clear vision such as driving or using machinery. The patient should limit alcoholic beverages.
- This medication can increase the risk of heat stroke. The patient should avoid activities that may lead to overheat (e.g., doing strenuous work, exercising in hot weather, or using a hot tub). The patient should drink plenty of fluids, dress lightly and stay in cooler/air-conditioned areas when the weather is hot.
- This drug may infrequently increase the blood sugar level, causing or worsening diabetes. Rarely, very serious conditions such as diabetic coma may occur.
- Liquid preparations of this product may contain sugar. Caution is advised if the patient has diabetes.
- This medication should be used only when clearly needed during pregnancy. The patient should discuss the risks and benefits with the doctor before using this medication during pregnancy.
- It is not known whether this medication passes into breast milk. Breast-feeding while using this drug is not recommended. Consultation should be done with the doctor before breast-feeding.
